Endocrine Abstracts

The aim of the study was to determine the clinical, immunological and genetics markers of latent autoimmune diabetes of adults (LADA) in early terms of disease development.Materials and methods: Seventy-eight LADA patients (47 women, 31 men, age of manifestation 45.52±1.83 years, average age 49.37±1.17 years, insulindependence age 49.33±0.34 years with anti islet, GADA antibodies and low C-peptide levels) were enrolled. The GADA, IA2A and ...

Aim: The aim of the study was to analyze the nodular goiter (NG) natural selection features in modern terms.Materials and methods: The average fertility indices per person, 211 patients with NG from the female cohort of Kharkov (eastern Ukraine) inhabitants, years of birth – 1925–1950, mean age – 58.6±0.5 years with the physiological cessation of fertility and 2105 normal healthy ones were analyzed. The dead (Pd) and...

Introduction: The role of the pineal gland and its hormone, melatonin, in the regulation of hypothalamo-adenohypophysial system activity is well known. At the same time, studies of the circadian rhythm of melatonin secretion in patients with pituitary adenomas are few in number, because the evaluation of pineal activity is not generally included in the clinical investigation of patients with pituitary tumors.Aim: The present study analyzed the circadian ...